Once changed in the Print Selection Panel of a report, the new font definitions should be saved and available across future Quicken sessions.
You may want to try the following:
How to Repair Printer Setup:
Try resetting your printer definitions in Quicken and then redefine the printer:
For Quicken for Windows versions 2009 and older:
For Quicken for Windows 2010 until Quicken Subscription (US, 2021) R33:
For Quicken for Windows Subscription (US, 2021) R34 and newer:
Printer Setup (all versions):
If you're printing checks, do not forget to select the correct check style.
Additional things to check:
No. You select the font style to use when printing in your Excel program. In Excel, look for File Menu / Options / "When creating new workbooks use this font:" and choose your new default font style and size.