Same issue w/in Q or on the web. Fields are locked. Was able to change the street address.
[Edited - Readability]
@John Patriarca I noticed from your other post that your Validate report showed several issues and that your Online Backup is also failing. While those issues may not be directly related to the inability to update your City, State, and ZIP information, they do suggest there may be more going on than a simple profile-editing problem.
While I don't think this issue is necessarily related to the problems shown in your Validate report or the Online Backup failures, the fact that you're experiencing multiple issues at the same time suggests it would be a good idea to contact Quicken Support. They have access to account-level information and can investigate whether there is a problem with your Quicken Account profile, as well as help determine if the backup failures and validation issues indicate a broader problem that needs to be addressed.
10-4.
Disregard. When one selects the proper drop down street address, the other field self populate with the correct city, state and zip.