If you haven't rebooted Windows since you installed the latest software update, please do so now and then try Quicken again.
Still not working?
Please perform the steps in this document:Troubleshooting 101 - Fixing Software Installation and Data File Problems
If that still doesn't fix the problem, I'd say it's time to call Quicken Support on the phone and request help. Let them do a screen share session with you to review the situation on your computer, to determine the nature of the problem and to figure out how to fix it.
Quicken Support: