I am having the same issue Currently on R50.15, Build 27.1.50.15 on Windows 10 Enterprise, but have had this issue for all prior releases for a long time.
Do you have any kind of error messages when that happens? Is Windows running out of memory, real or virtual? How much RAM do you have installed? How much does Windows Task Manager say is in use at that time? >80%? Is the Windows Paging File large enough to accommodate your workload? I'd suggest RAM GB * 2 or more.
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