Are you Syncing to Mobile/Web? AND do you use the Mobile app on your smartphone or the Quicken on the Web feature?
If you answer "no" to both, turn Sync off completely. You don't need it.
If yes, try to Reset Sync so that the current cloud sync file is replaced with a fresh complete copy Do note that a full Sync process may take many minutes to complete.
Log out of your mobile app, then do this on your desktop / laptop:
How to reset Sync to Cloud
How to turn off Sync to Cloud for the current data file
Also see https://www.quicken.com/support/troubleshooting-quicken-mobile-companion-app and https://community.quicken.com/discussion/7856172/faq-common-mobile-web-sync-errors-and-solutions#latest
If you haven't rebooted Windows since you installed the latest software update, please do so now and then try Quicken again.
Still not working?
Let's try some "Troubleshooting 101" to ensure the Quicken software is installed and updated properly and that your data file is in good working order. Please perform all the steps in this document:Troubleshooting 101 - Fixing Software Installation and Data File Problems
Jeffrey Wilens said: Memorized payee list is completely blank but it should have hundreds of entries. This is after updating to Quicken for Windows 24.14. Don't want to use a backup since already did a lot of downloading and entries. Is this broken again?